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Tamoxifen handling

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  1. Smer4ik Well-Known Member

    Tamoxifen handling


    Well, I finished radiation this week and all went very well with no issues at all. I have some other medical issues that need to be addressed while undergoing this treatment, so I may have to start on Tamoxifen before going on an AI . I am postmenopausal, so I don't need to worry about that. I am postmenopausal and initially started on an AI. I switched to Tamoxifen at about 2 years just to see if my lack of hair might be due to the AIs. But I stayed on Tamoxifen for the duration because I tolerated it well and because my bone density actually improved, after diminishing on the AI (and I just didn't want to take a bisphosphonate yet). Remember, not too many years ago, Tamoxifen was used for all women because the AIs had not been perfected yet. I think the AIs might be "better" for postmenopausal women, but better than what? I stopped at 5 years rather than continue for the now recommended 10. 5 years is what was recommended to me when I began and I just didn't want to take it longer. Had it been a higher stage and grade, I would have taken it for the now recommended 10 years without question. For me we decided that the risks of being on the drug was greater than my risk of recurrence at this point. I have had hot flashes but I am also going through natural menopause as well as being in the middle of six weeks of radiation treatment. I did well with absolutely no side effects on both the AI and Tamoxifen and I'm very happy about all of that. This is what I was told at the time of my switch from AI to Tamoxifen. zoloft energy Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Also tell your doctor if you smoke, if you have high blood pressure or diabetes, if your ability to move around during your waking hours is limited, or if you are taking anticoagulants ('blood thinners') such as warfarin (Coumadin). If you experience any of the following symptoms during or after your treatment, call your doctor immediately: abnormal vaginal bleeding; irregular menstrual periods; changes in vaginal discharge, especially if the discharge becomes bloody, brown, or rusty; pain or pressure in the pelvis (the stomach area below the belly button); leg swelling or tenderness; chest pain; shortness of breath; coughing up blood; sudden weakness, tingling, or numbness in your face, arm, or leg, especially on one side of your body; sudden confusion; difficulty speaking or understanding; sudden difficulty seeing in one or both eyes; sudden difficulty walking; dizziness; loss of balance or coordination; or sudden severe headache. You will need to have gynecological examinations (examinations of the female organs) regularly to find early signs of cancer of the uterus. If you are thinking about taking tamoxifen to reduce the chance that you will develop breast cancer, you should talk to your doctor about the risks and benefits of this treatment. You and your doctor will decide whether the possible benefit of tamoxifen treatment is worth the risks of taking the medication. If you need to take tamoxifen to treat breast cancer, the benefits of tamoxifen outweigh the risks. Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with tamoxifen and each time you refill your prescription.

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    Tamoxifen is a toxic substance, and hazardous in case of skin contact irritant, eye contact, and ingestion and inhalation 5. Any sharp cutting instruments and needles for chemical adminstration into animals must be properly cleaned and laid out in such a way to allow easy work flow and prevent injury Section 3 – Procedure Handling and. buy celebrex pfizer Apr 10, 2014. The information related to health risks to foetuses due to the handling of chemotherapeutic agents by nurses during pregnancy is limited. To prevent skin exposure, appropriate personal protective equipment PPE must be worn when handling any amount of Tamoxifen in the lab or SC-510.

    The Office of Environmental Health and Safety Boston University OEHS POLICIES AND GUIDELINESTITLE: Tamoxifen Treatment in Animals. Tamoxifen is a synthetic chemical which is most commonly used to treat Breast Cancer in women. Besides these cancer treatments, Tamoxifen is administered into animals as a research tool to trigger tissue-specific gene expression in many conditional expression constructs of genetically modified animals. Tamoxifen is a known human carcinogen, teratogen, and mutagen. When working with Tamoxifen in laboratories outside of animal facilities, PPE should include, at a minimum, a lab coat, double Nitrile gloves, and ANSI Z-87 compliant protective eyewear that provides chemical splash protection and appropriate lab attire (full-length pants, closed toe shoes, etc.)Whenever the potential for aerosolization of prepared Tamoxifen solutions exists, procedures should be done in an appropriate containment device, such as a chemical fume hood. Outside of containment, an N95 respirator should be worn whenever the potential for inhalation exists. Note that the use of an N95 respirator requires medical clearance and fit testing to comply with .134. Net Podcast: How to Safely Handle and Dispose Medication. During and after cancer treatment, people may have 1 or more medications to take at home. These powerful medications can be very harmful if someone other than the person with cancer takes them. Therefore, you and your caregivers need to know the safest ways to store and dispose of specific medications. People diagnosed with cancer often experience pain, either from the cancer itself or as a side effect of treatment. As a result, managing and treating pain is an important part of a person’s overall treatment plan. This may involve the use of pain-relief medications called analgesics.

    Tamoxifen handling

    Laboratory-Specific Standard Operating Procedures TITLE SOP for., Is it safe for pregnant health-care professionals to handle cytotoxic.

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  3. Agency for Research on Cancer IARC lists Tamoxifen as a known human. Occupational Health See 5.6.2 prior to handling Tamoxifen or animals that have.

    • Guidelines for the use of tamoxifen in animal. - Western University
    • Research Using Tamoxifen in SC-510 Animal Resource.
    • Tamoxifen MedlinePlus Drug Information

    Special handling of pain medication. People diagnosed with cancer often experience pain, either from the cancer itself or as a side effect of treatment. As a result. diflucan 100mg The initial order for Tamoxifen should be written on a pre-printed order; if not. When handling this drug, disposable gloves should be worn at all times by any. Store Tamoxifen at room temperature, protect it from light and moisture and keep it away from children.

     
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