I have been using Propecia since it became available on the market, which is quite a few years. Have there been any adverse effects of using Propecia over a long period of time? Concerned, Jason – – – – – – – – – – – Dear Jason, Finasteride was first approved by the FDA in 1992 as Proscar. As you’re probably aware, Proscar is a 5 mg dosage of Finsateride that is proscribed for the treatment of BPH or prostate enlargement. The 1 mg dose of finasteride, approved as Propecia in December of 1997, was the first truly effective treatment for male pattern hair loss. To my knowledge, in the sixteen years that finsateride has been on the market there have been no reports of any adverse effects on the liver of those using the drug for an extended period of time. As always, I have to state clearly that I am not a physician and that my opinions and knowledge concerning hair loss and its treatments are based on extensive research and reporting on the subject as a consumer advocate and hair loss educator. With this said, it’s important to note that Propecia cuts PSA levels in half after one year of use. buy cipro in mexico Finasteride is used to treat men with benign prostatic hyperplasia (BPH) and male pattern hair loss, also called androgenetic alopecia. Men with BPH usually have difficulty urinating, a decreased flow of urination, hesitation at the beginning of urination, and a need to get up at night to urinate. Finasteride will make these symptoms less severe and reduce the chance that prostate surgery will be needed. It may be used alone or in combination with other medicines such as an alpha-blocker (doxazosin, Cardura®) to treat BPH. For men with hair loss, finasteride will increase the number of scalp hairs but will not increase the amount of body hair. Finasteride blocks the action of an enzyme called 5-alpha-reductase. This enzyme changes testosterone to another hormone that causes the prostate to grow or hair loss in males. It will increase testosterone levels in the body, which decreases prostate size and increases hair growth on the scalp. Zithromax acne Jun 22, 2017. risk for diabetes, elevated cholesterol levels, non-alcoholic fatty liver. and improves urination or other drugs such as Proscar Finasteride or. viagra symptoms Liver Enzymes High extremely common side effect of duta ! took me a while to know this and have being high since I started 15 years ago. Hello, I just got back blood work and my liver enzymes are off the chart. My AST is 246 and my ALT is 118. I'm very concerned that my liver is damaged for good. Treatment of benign prostatic hyperplasia (BPH) with the commonly prescribed Avodart (Dutsteride) may put men at an increased risk for diabetes, elevated cholesterol levels, non-alcoholic fatty liver disease (NAFLD) and worsening erectile dysfunction. This condition often results in urinary retention or other lower urinary tract symptoms, such as reduced urinary flow leading to waking up several times at night to urinate. Physicians should be fully aware of these new findings according to the researchers, and to discuss with their patients the potential adverse side effects of Avodart on metabolic and sexual function before prescribing it. To help improve symptoms, men are often prescribed an alpha blocker, such as Tamsulosin (Flomax) which relaxes the prostate smooth muscle and improves urination or other drugs such as Proscar (Finasteride) or Avodart (Dutsteride) which work by reducing prostate volume thus, improving urinary function. “We believe our findings suggest that Avodart has a negative impact on men’s overall health since it increases blood sugar and A1C and also increases blood lipids. The increase in blood glucose and A1C may predispose men to diabetes and the increase in lipids may predispose them to NAFLD. Most importantly, this agent worsens sexual function and reduces quality of life,” explained corresponding author Abdulmaged M. Traish, Ph D, MBA, professor of biochemistry and urology at BUSM. This retrospective study included one group of men with BPH who were prescribed Avodart and a second group who were prescribed Tamsulosin (an alpha blocker). Data on blood glucose, hemoglobin A1C, total cholesterol, LDL cholesterol (bad cholesterol), HDL cholesterol (good cholesterol), liver function enzymes were determined at each visit over the entire follow up period. In some cases, they may not be available in every strength or form as the brand-name drug. Finasteride oral tablet is available as the brand-name drugs Proscar and Propecia. Generic drugs usually cost less than the brand-name version. The condition that finasteride is used to treat depends on the type of the drug used. Finasteride isn’t prescribed for use in women or children. Finasteride works by decreasing the amount of the hormone dihydrotestosterone (DHT) in your body. The decrease in DHT helps prevent your prostate from growing larger. It also leads to increased hair growth and decreased hair loss of the hair on your head. Hair growth on other parts of the body isn’t affected. 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If you have liver disease, your body might process this drug more slowly. where to buy retin a cream uk Liver damage - cbsnews.comBlood tests showed elevated liver enzymes indicating liver damage, The doctors believe that high levels of vitamin B3, or niacin, Genzyme's Mipomersen Liver Side Effects Could Limit a Genzyme's Mipomersen Liver Side Effects Could Limit a Promising Cholesterol Drug. for increases in stores of hepatic fat and elevated liver enzymes. Learn about Propecia Finasteride may treat, uses, dosage, side effects, drug. in the liver, primarily via the cytochrome P450 3A4 enzyme subfamily.