Chemical Name: ACYCLOVIR (ay-SYE-kloe-veer) Zovirax Cream 5% (Acyclovir) Acyclovir cream is an anti-viral drug and is used to treat viral infections and its symptoms. It may be used to treat viral diseases such as herpes, particularly cold sores, shingles, and chicken pox. Zovirax will not cure these diseases, and the virus will continue to live within the body. This medicine works by lowering outbursts of symptoms. It decreases itching, prevents new sores from forming, helps quicken the healing process, etc. It is also helpful for people with a weakened immune system to fight off diseases. 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