Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and oral thrush Has anyone been treated on just sulfasalazine and plaquenil Chloroquine malaria side effects Summary Interstitial lung disease is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Much like acute pneumonitis, there are two ways in which pulmonary hypertension can develop with someone who has lupus. 1 Pulmonary hypertension involves an increased pressure in the blood vessels inside the lung. When blood goes into the lungs, Dr. Kaner explained, it first goes into the right ventricle. Lung infections are the most common cause of lung nodules as they lead to the growth of lung tissue and inflammation. Infections like tuberculosis can cause inflammation. When granuloma cells form around the area of inflammation in the lungs, it can create a lung nodule. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause lung problems Hydroxychloroquine Plaquenil Side Effects & Dosage for., Pulmonary Conditions & Lung Problems in People With Lupus Plaquenil and coffeeHydroxychloroquine and cyclobenzaprineIs plaquenil the same as hydroxychloroquineLosing weight off of plaquenil Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. The Risks, Symptoms, Treatments & Causes of Lung Nodules.. Will you have Idiopathic pulmonary fibrosis with Plaquenil.. I am surprised they would call out plaquenil instead of the methotrexate. Methotrexate side effects include lung issues like pleuropulmonary issues which symptoms include a nonproductive cough and dyspnea. It also can create fibroids, lesions, and various other respiratory issues even though in high does it can be used to treat lung cancer. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus SLE. It wasn't as severe as it was when I was a child until I started Plaquenil. When I started Plaquenil almost 2 months ago I assumed the GI issues were a side effect and it would eventually go away but it hasn't. I'm going to bring it up to my rheumy when I see him. For now I'm trying to avoid dairy the best I can. I gave in today and had a shake.