Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Do chloroquine cause splenomegaly Chloroquine phosphate freshwater fish Side effects of prednisone that are different from Plaquenil include acne, thinning skin, weight gain, restlessness, and trouble sleeping. Both Plaquenil and prednisone may interact with antibiotics, tuberculosis medications, nonsteroidal anti- inflammatory drugs NSAIDs, HIV / AIDS medications, estrogens including oral contraceptives or hormone replacement therapy, or seizure medications. Summary Drug interactions are reported among people who take Prednisone and Plaquenil together. This study is created by eHealthMe based on reports of 13,794 people who take Prednisone and Plaquenil from Food and Drug Administration FDA, and is updated regularly. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and prednisone interaction Plaquenil hydroxychloroquine sulfate dose, indications., Prednisone and Plaquenil drug interactions - eHealthMe Plaquenil increased gasPlaquenil and hair growthAccidently took next days dose of hydroxychloroquine Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Prednisone and Plaquenil question" Lupus Community.. Plaquenil vs. Prednisone Prescription Treatment for.. More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. If common side effects do occur, they are usually minor and last only for a short period of time. Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in three categories common, less common, and rare. Aug 22, 2008 I take both prednisone and plaquenil. I heard someone once say that prednisone is the drug one loves to hate. It really does wonders to control inflammation, but has nasty side effects when given in large doses and/or used for a long period of time. My first experience with prednisone was horrific I was on 60mg per day, then on to 50, then 40.