It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Retinal changes with the use of hydroxychloroquine A patient will begin taking hydroxychloroquine for rheumatoid arthritis Methotrexate sulfasalazine hydroxychloroquine and leflunomide I take methotrexate injections weekly along with antibotic thereaphy of 200 mg of minocycline. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. Kids shouldn't take Plaquenil as a long-term treatment. warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil safe to take Protecting your eyesight when taking Plaquenil Lupus., Plaquenil Hydroxychloroquine - Side Effects, Dosage. What else can i take if i cant take plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Does Plaquenil Interact with other Medications? Severe Interactions. nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone. Aug 29, 2014 Recent findings suggest that Plaquenil toxicity can develop among patients that are taking the drug at a daily dose lower than the suggested “safe” dose and/or have been on Plaquenil for shorter than five years.