One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Generic hydroxychloroquine generic Substitute for hydroxychloroquine Does plaquenil interact with alcohol Plaquenil and aleve Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Plaquenil, or hydroxychloroquine, is an anti-malaria medication that is commonly used to treat autoimmune disorders like lupus or rheumatoid arthritis. During World War II, it was found that antimalarial drugs helped improve fatigue, fever and skin rashes as well as joint and muscle pain, which are common symptoms in lupus. While Plaquenil can cause toxicity damage to the macula, it will not cause a macular pucker. If you are on Plaquenil, it is recommended that you have your retina checked regularly by an ophthalmologist, including imaging studies, which can help find damage to the macula. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Plaquenil use in macular degen Multimodal Imaging in Plaquenil Toxicity, Focus on Eyes Long-term Macular Degeneration Association Structure activity relationship of chloroquine pptHydroxychloroquine sul tabs 200 mg Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. The Risk of Retinal Toxicity with Plaquenil. Can Plaquenil cause a macular pucker? - American Academy.. Plaquenil - FDA prescribing information, side effects and uses. Plaquenil and Macular degeneration - a real-world study. Summary Macular degeneration is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take medication Humira, and have Joint deposit. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3 The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Focus on Eyes Long-term Plaquenil intake can affect your vision by Dr. Juan Carlos de Rivero Vaccari and Dr. Frederick Ho, Special to FLORIDA TODAY Plaquenil, or hydroxychloroquine, is an anti-malaria medication that is commonly used to treat autoimmune disorders.