Chloroquine hydrochloride

Discussion in 'Hydroxychloroquine Sulfate' started by bku, 23-Feb-2020.

  1. zet XenForo Moderator

    Chloroquine hydrochloride


    In certain countries and parts of the world where malaria is still present, a person can easily catch malaria from a seemingly insignificant mosquito bite. These medications are primarily designed to treat the strains of malaria linked with mosquito bites, but there are a few alternate uses for these medications outside the scope of treating malaria infections.

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    Action Date Submission Action Type Submission Classification Review Priority; Orphan Status Letters, Reviews, Labels, Patient Package Insert Notes Chloroquine hydrochloride Injection 50 mg/ml 40 mg/ml base chloroquine phosphate Tablets 250 mg 150-mg base; 500 mg 300-mg base Indications and dosages Suppressive prophylaxis. Adults 500 mg 300-mg base P. O. on same day once weekly beginning 2 weeks before exposure. Chloroquine Hydrochloride is the hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum.

    It belongs to a disease-modifying antirheumatic drug classification. Combined with other medications, hydroxychloroquine is often used as part of a treatment plan for a host of auto-immune diseases, such as rheumatoid arthritis and lupus.

    Chloroquine hydrochloride

    Chloroquine, Chloroquine Tablets, Aralen Phosphate., Chloroquine hydrochloride - GLOWM

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  6. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious

    • Chloroquine - Wikipedia.
    • Chloroquine hydrochloride C18H28Cl3N3 - PubChem.
    • Chloroquine hydrochloride definition of chloroquine..

    Quinine remained the antimalarial drug of choice until after World War II, when other drugs, such as chloroquine, that have fewer side effects largely replaced it. Bromo Quinine were brand name cold tablets containing quinine, manufactured by Grove Laboratories. They were first marketed in 1889 and available until at least the 1960s. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Chloroquine-resistant strains have been reported. Also acts as a tissue amebicide, has antiinflammatory, antihistamine, and antiserotonic properties. Uses. Suppression and treatment of malaria caused by P. malariae, P. ovale, P. vivax, and susceptible forms of P. falciparum, and in the treatment of extraintestinal amebiasis.

     
  7. Dewei Well-Known Member

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  9. kkap Well-Known Member

    Chloroquine - an overview ScienceDirect Topics The aminoalkyl side chain in chloroquine helps in the accumulation of the drug inside the food vacuole and assists in the complexation of the quinoline nucleus with the porphyrin system. Modification of this side chain either by varying its length or attaching new chemical groups can circumvent chloroquine resistance.

    Inhibitory Activity of Ferroquine, versus Chloroquine.
     
  10. kdg1936 Guest

    Chloroquine Clinical Trials, Side Effects AIDSinfo Chloroquine is being investigated studied to treat HIV infection. As an HIV investigational drug, chloroquine is categorized as an immune modulator. 2 Immune modulators also called immunomodulators are substances that help to activate, boost, or restore normal immune function.

    Chloroquine C18H26ClN3 - PubChem