It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and diabetes Plaquenil exfoliative dermatitis Jan 03, 2020 Plaquenil Dosage Malaria. Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior. Lupus Erythematosus. The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Upsides. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil dosage forms PLAQUENIL hydroxychloroquine sulfate Label, Plaquenil hydroxychloroquine Basics, Side Effects. Chloroquine mnemonicHydroxychloroquine plaquenil usesPharmacokinetics of chloroquine Recommended doses of the medication vary according to the condition being treated. Rheumatoid arthritis The usual adult starting dose is 400 mg to 600 mg daily. It may take several weeks before the beneficial effects of hydroxychloroquine for the treatment of rheumatoid arthritis are seen. Plaquenil - Uses, Side Effects, Interactions -. Hydroxychloroquine Oral Route Description and Brand.. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Feb 19, 2020 Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Case reports describe dosage regimens that are effective yet tolerated, such as 12.5 mg PO twice weekly over 2 yr in a child aged 4-6 yr, and 100 mg PO twice weekly over 5 months in a child aged 12.