Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine and dormancy Hydroxychloroquine pulmonary fibrosis Hydroxychloroquine or Plaquenil is felt to be safe during the preoperative period. It is recommended to continue this medication without stopping," Dr. Grant said. Long-term use can cause cataracts and increase the risk of glaucoma. Antimalarials. Plaquenil can occasionally cause decreased vision. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil cataracts Hydroxychloroquine Side Effects, Dosage, Uses, and More, Vision Problems and Autoimmune Disorders - Autoimmune. Eye things behind eye from taking plaquenilAralen contraindicationsPlaquenil with percocetHydroxychloroquine aoa Significant cataracts can affect the outcome of the mfERG12 • In studies, 20-60% of patients receiving Plaquenil were found to have mfERG abnormalities—however, clinically significant hydroxychloroquine Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil Toxicity with a bullseye pattern of central pigment loss. The risk of macular damage is dependent on the daily dose and duration of use, although kidney disease and tamoxifen increase this risk. At recommended doses, the risk of toxicity up to 5 years is under 1%, under 2% up to 10 years. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Plaquenil, also known as hydroxychloroquine, is a disease-modifying anti-rheumatic drug DMARD used to reduce inflammation and decrease pain caused by certain forms of arthritis and autoimmune disorders, such as rheumatoid arthritis and lupus.