Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine and parkinson's disease Hydroxychloroquine muscle wasting ARALEN is an antimalarial and amebicidal drug. Chemically, it is 7-chloro-4-4-diethylamino-1-methylbutylamino quinoline phosphate 12 and has the following structural formula Each tablet contains 500 mg of chloroquine phosphate USP, equivalent to 300 mg chloroquine base. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. The drug chloroquine is bactericidal for Bacillus megaterium ; it inhibits DNA and RNA biosynthesis and produces rapid degradation of ribosomes and dissimilation of ribosomal RNA. Inhibition of protein synthesis is also observed, evidently as a secondary effect. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine drug action Hydroxychloroquine Plaquenil Side Effects & Dosage for., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Chloroquine phosphate synthesisTeva-chloroquine phosphateChloroquine phosphate where to buyHydroxychloroquine 200 mg tab couponHydroxychloroquine and t cells Drug interactions Antacids - may reduce absorption of chloroquine. Kaolin - may reduce absorption of chloroquine. Cimetidine - may inhibit metabolism of chloroquine; increasing levels of chloroquine in the body. Ampicillin - levels may be reduced by chloroquine. Cyclosporine - levels may be. Chloroquine - Wikipedia. Chloroquine Mode of Action Science. Chloroquine C18H26ClN3 - PubChem. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus. These compounds lead to improvement of clinical and laboratory parameters, but their slow onset of action distinguishes them from glucocorticoids and nonsteroidal antiinflammatory agents. Summary. Aralen is the brand name for the generic drug chloroquine, an anti-malaria drug used to treat malaria and amebiasis infection that's spread outside of the intestines. Dosage, drug interactions, and pregnancy and breastfeeding safety information should be reviewed prior to taking this drug. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects Treatment for malaria can be done by various drugs, in this specific.