These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine manufacturer Symptoms of plaquenil toxicity Purifying chloroquine phospahte This sort of retinal damage may result in patchy loss of central vision or patchy loss of vision just close to the centre of your vision. There are a number of other much less important side effects of Plaquenil, including changes in the cornea and changes in the eyelids. Retinal toxicity is a very rare side effect of the hydroxychloroquine therapy, but when it has occurred, vision loss may be permanent and may progress even years after the cessation of medication. Patients would be examined every 3 months, then annually, until they are stabled. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil color vision effects Plaquenil Hydroxychloroquine - Side Effects, Dosage., Retinal toxicity associated with chronic exposure to. Hydroxychloroquine and retinal depositHydroxychloroquine guidelines Patients in earlier stages of hydroxychloroquine retinal toxicity usually do not experience symptoms, though the rare patient may note a paracentral scotoma that causes trouble with reading as well as diminished color vision. However, most patients usually notice symptoms only after scotomas have become severe. Hydroxychloroquine-Induced Retinal Toxicity - American.. Rx Side Effects New Plaquenil Guidelines and More.. What Is Plaquenil? - American Academy of Ophthalmology. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. blue-black skin color;. which can increase the risk of side effects, including vision damage. Older.