He reported a history of tick bite and rash in 2002. The knee pain and other symptoms rapidly improved over the next two weeks. He received a short course of antibiotics at that time. After two weeks he reported that the antibiotics were causing nightmares and insomnia. Then one week later he complained of confusion and unsteadiness. How quick will symptoms return after you stop plaquenil Are you more like to get sick while take hydroxychloroquine In rheumatoid arthritis, hydroxychloroquine is known as a DMARD, or disease modifying antirhuematic drug. The drug improves joint mobility, decreases swelling and tenderness, but symptom improvement can take up to 6 months. User Reviews for Plaquenil to treat Lyme Disease, Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Because the symptoms are so variable, patients are usually not even considered for testing or treatment. Even if testing is done, however, standard testing will miss over 90% of cases of chronic Lyme disease. The standard testing is an immunoassay test of IgG and IgM antibodies and then a Western blot for confirmation. He continued to improve rapidly once more with a cessation of neurocognitive symptoms. When I saw him initially he complained of knee pain and swelling, fatigue, generalized arthralgia (joint pain), numbness and tingling and an irregular heart beat. I diagnosed a "brain Herx." I added Plaquenil back, as well as Welchol, presumptively to remove "neurotoxins." I also reduced the dose of Amoxicillin and Minocin. Plaquenil and lyme disease Hydroxychloroquine Plaquenil, Plaquenil User Reviews for Lyme Disease, Arthritis at Chemical structure of chloroquineDeschloroquine used on chloroquine resistant parasitesPlaquenil mayoclinic Lyme disease is the most common vector-borne disease in the Northern Hemisphere. It is now one of the fastest growing infectious diseases in the U. S. Lyme disease is caused by infection with the Borrelia burgdorferi bacteria, and is primarily transmitted to humans as well as dogs, horses and other domesticated animals by the bite of infected ticks. Ever take Plaquenil? DailyStrength. Dr. Holtorf on Lyme Disease Diagnosis and Treatment - A.. Will plaquenil kill the encysted form of lyme? Buhner.. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Lyme disease and for what kind of people. The study is created by eHealthMe from 7 Plaquenil users and is updated continuously. Lyme arthritis was originally recognized because of an outbreak of monoarticular and oligoarticular arthritis in children in Lyme, Connecticut in the 1970s. 1 It then became apparent that Lyme disease was a complex multisystem illness affecting primarily skin, nervous system, heart or joints. 2 Prior to the use of antibiotic therapy for. If however you have lyme bad enough to be on months of plaquenil, isn't it almost better to be getting the treatment with some bad dreams, than having no bad dreams but continuing with lyme disease? Unless of couse you can switch to another that'll work as well clarythromicin has worked well.