Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Why is hydroxychloroquine so expensive Plaquenil help with fatigue What are the side effects from stopping taking plaquenil Plaquenil equivalent Aug 01, 2009 I've been on it for almost 3 years and my weight gain is due to me seeking comfort from the pain by eating too much sweets. Joy. Lupus, Fibromyalgia, Glaucoma, Asthma, Hypothyriodism, Sleep Apnea, Degenerative Disk and Facet Disease, and Allergies. When life throws you lemons. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. I started Plaquenil in Feb. I'm anti meds but the time came to try improve quality of my life. The side effects in the 1st week were amplified fatigue & nausea for a good month. I kept taking them & now I don't have any side effects. My energy much better, no more daytime napping needed optition side the retina toxification is very rare. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Side effects of hydroxychloroquine weight gain Hydroxychloroquine and weight gain - Answers on HealthTap, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Does plaquenil cause coughingHydroxychloroquine sulfate and hydroxychloroquine sulfate plaquenilChloroquine phosphate where to buy Side effects Mild nausea, constipation, headaches, dizziness, tinnitus Evaluations from Patients who take Hydroxychloroquine PatientsLikeMe. How good is Hydroxychloroquine, and any side. - HealthUnlocked. Hydroxychloroquine Side Effects - GoodRx. If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. During trials, if any adverse event read possible side effect occurs, and the company can't prove it wasn't the drug, it goes on the list as a side effect. The more common side effects that can occur with hydroxychloroquine include headache. dizziness. diarrhea. stomach cramps. vomiting. Weight increased is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have High blood pressure.