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    This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine.

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    Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory.

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    Chloroquine is a lysosomotropic agent that prevents endosomal acidification [1]. Chloroquine inhibits autophagic flux by decreasing autophagosome. Recent insights into the function of autophagy in cancer The Roles of Therapy-Induced Autophagy and Necrosis in Cancer.
     
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    Drug Toxicity to the Retina and Optic Nerve Are You Missing. Hydroxychloroquine Plaquenil is a disease-modifying antirheumatic drug that is commonly used to reduce arthritic pain and swelling. Signs and symptoms. “The associa­tion of Plaquenil therapy with mac­ular toxicity is well established,” said Michael F. Marmor, MD, at the Byers Eye Institute at Stanford University.

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