Chloroquine brain cancer

Discussion in 'Chloroquine Pills' started by krilay-k, 08-Mar-2020.

  1. Buyanka XenForo Moderator

    Chloroquine brain cancer


    Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties.

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    Aug 27, 2018 Glioblastoma is one of the most aggressive human cancers shown to have a better response to standard therapy when combined with chloroquine. While there is considerable evidence for the efficacy and safety of chloroquine as an adjuvant treatment for cancer, the mechanisms underlying the tumor suppressive actions of this drug remain elusive. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P. malariae, P. ovale, and P. vivax. Prophylaxis of malaria in geographic areas without resistance to chloroquine.

    In cancer, authophagy is the process used by cancer cells to “self-eat” in order to survive. Specifically, if authophagy is prolonged this will become a lethal process to cancer. duing chemotheraphy, radiotheraphy, etc.) authophagy is used by cancer cells to survive. However, note that Chloroquine has other properties as well that may be very well related to anti cancer mechanism, such as zinc ionophore, and others (see below the section on mechanisms).

    Chloroquine brain cancer

    Glioblastoma Treatment Breakthrough 'Untreatable' Brain., Chloroquine Oral Uses, Side Effects, Interactions, Pictures.

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  6. Nov 04, 2015 Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells Kazuhito Sasaki1*, Nelson H Tsuno12, Eiji Sunami1, Giichiro Tsurita1, Kazushige Kawai1,Yurai Okaji2, Takeshi Nishikawa1, Yasutaka Shuno1, Kumiko Hongo1, Masaya Hiyoshi1,Manabu Kaneko1, Joji Kitayama1, Koki Takahashi2 and Hirokazu Nagawa 2010 BMC Cancer Vol. 10.

    • Chloroquine plaquil combinations - Ovarian cancer - Inspire.
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    • Autophagy inhibition in cancer Clinical Trials Update Novus..

    Malaria Drug, Chloroquine, May Help Treat Brain Cancer. The anti-malaria drug, chloroquine, may now be a unique way to resensitize some cancer patients to treatment for brain cancer. The new study shows how the drug could be used to treat brain cancer patients. Jan 20, 2017 The anti-malaria drug chloroquine has now been used as a last resort on three brain cancer patients, and in each case, it seems to have overcome the cancer's resistance to traditional treatments. Chloroquine appears to break down the defences that tumours develop in response to cancer-fighting drugs by effectively 'resetting' their vulnerability to treatment. Oct 01, 2018 Chloroquine is deposited in the tissues in considerable amounts. In animals, from 200 to 700 times the plasma concentration may be found in the liver,spleen, kidney, and lung; leukocytes also concentrate the drug. The brain and spinal cord, in contrast, contain only 10 to 30 times the amount present in plasma.

     
  7. Seo1989 Moderator

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Uses, Dosage & Side Effects - Plaquenil Oral Interactions with Other Medication Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria
     
  8. Avelin_Bahtuzin XenForo Moderator

    In some cases, they may not be available in every strength or form as the brand-name drug. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil Side Effects on Your Eyes and Vision
     
  9. Yano4ka XenForo Moderator

    Chloroquine Indications, Side Effects, Warnings - A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen.

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