Bone mineral density problem #1: Glucocorticoids These wonder drugs work fast to fight inflammation from rheumatoid arthritis, lupus, fibromyalgia, Lyme disease, or a nasty rash from contact dermatitis. But they’re also the most common source of bone loss from medications, according to a 2010 joint study by the University of Colorado in Denver and the College of Pharmacy & Department of Medicine at Dalhousie University in Halifax. Is chloroquine available over the counter Aao 2016 plaquenil guidelines Hydroxychloroquine monitoring ophthalmology Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil and Osteoporosis - from FDA reports Summary Osteoporosis is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. With the plaquenil I saw a big reduction in brain fog, tiredness and flu like feeling and big increase in ability to concentrate. Hope to hear good news from you in another month or so. Comment A Canadian study, published in a 2013 issue of the journal Osteoporosis International, found that prolonged use of glucocorticoids within the last 12 months reduced bone mineral density and increased fracture risk in the participants.“The risk of bone loss continues for as long as women stay on glucocorticoids,” Wei says. Glucocorticoids (with brand names like Prednisone, Flovent, Actonel, Decadron, Aristocort and Depo-Medro) trigger gradual bone loss, by decreasing its formation, reducing calcium absorption in the intestine and increasing urinary excretion of calcium, an important skeletal nutrient. Can plaquenil cause bone loss Common and Rare Side Effects for Plaquenil Oral, Will you have Osteoporosis with Plaquenil - eHealthMe Hydroxychloroquine myopathyHydroxychloroquine other names The loss of calcium in the urine increases bone loss and fracture risk. In contrast, thiazide diuretics cause the kidney to hold on to calcium, and tend to increase bone density. There is also research that connects the use of some loop diuretics with falls and increases the risk of spine fractures. To lessen the harm to the bones from loop diuretics Medications That Can Be Bad for Your Bones - American Bone Health. Plaquenil Hydroxycholorquine - Arthritis - MedHelp. Plaquenil Side Effects Common, Severe, Long Term -. To begin with, the glucocorticoid medications often prescribed to treat SLE can trigger significant bone loss. In addition, pain and fatigue caused by the disease can result in inactivity, further increasing osteoporosis risk. Studies also show that bone loss in lupus may occur as a direct result of the disease. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Even low daily doses 2.5 mg can cause bone loss, and anyone taking more than 7.5 mg a day” – for diseases like rheumatoid arthritis, lupus, multiple sclerosis and inflammatory bowel.