Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Take plaquenil with vitamins Plaquenil and iron supplements Chloroquine diphosphate 25 μm Folic acid is the manufactured form of folate. Taking folic acid can help to make up for, or supplement, the folate that your body loses when you take methotrexate. Hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. Background 34 year old mother of 2 diagnosed in December with RA high RF and Anti-CCP. I'm on methotrexate injections just recently increased to 20 mg and plaquenil 200 mg twice a day. And folic acid. Early December I received a steroid injection to help with the pain/inflammation and improve my mobility temporarily. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and folic acid interactions Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Methotrexate and plaquenil - Hydroxychloroquine sulfate tablets 400mg Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. or herbs you may be taking. An interaction is. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Side effects plaquenil/methotrexate. rheumatoid. Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs.. FOLIC ACID TabletDESCRIPTION. Folic acid, USP, N-p-2-amino-4- hydroxy-6-pteridinyl methyl- amino benzoyl-Lglutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic acid. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The different treatment schedules with folic acid can lead to questions as to what is the right one. Rheumatologist Scott Zashin, a clinical assistant professor at the University of Texas Southwestern Medical School says, "I have my patients take it daily, including the day of methotrexate.