Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Hydroxychloroquine side effects medbullets Plaquenil side effects skin discoloration Chloroquine diphosphate salt Plaquenil eye exam frequency The effects of methotrexate and hydroxychloroquine combination therapy vs methotrexate monotherapy in early rheumatoid arthritis patients Lisa Schapink. Department of Rheumatology, Sint Maartenskliniek, the Netherlands. Department of Rheumatology, Radboudumc, Nijmegen, the Netherlands. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Methotrexate or plaquenil Methotrexate or Plaquenil - Scleroderma - Inspire, Methotrexate vs Plaquenil Comparison - Plaquenil chronic hivesHydroxychloroquine and epsom salt bathChloroquine fisher Jul 18, 2014 Cardiovascular risk evaluation. Prior to elective surgery, the risk of perioperative cardiovascular events must be assessed. Overall, individuals with rheumatoid arthritis have a higher risk of myocardial infarction which is similar to individuals with diabetes mellitus or a person 10 years older than the age of the patient. Perioperative management of the patient with rheumatoid arthritis. Does anyone take methotrexate and hydroxychloroquine. - NRAS. Methotrexate vs plaquenil side effects long term and short term. Plaquenil and Rheumatrex and Trexall belong to different drug classes. Plaquenil is an antimalarial medication and Rheumatrex and Trexall are antimetabolite drugs. Side effects of Plaquenil and Rheumatrex and Trexall that are similar include nausea, vomiting, dizziness, or headache. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks.