Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Chloroquine dosage Hydroxychloroquine muscle wasting Hydroxychloroquine copay assistance program Does plaquenil ease symptoms of ms and als In addition, lenalidomide may be useful in some patients. 30 Hydroxychloroquine is the first-line systemic agent for discoid lupus erythematosus DLE, whereas chloroquine is considered. The treatment of cutaneous lupus erythematosus is centered upon formulating a regimen of topical and systemic therapies designed to reduce disease activity and minimize cosmetic damage. Sun avoidance and sunscreen are important preventative measures proven to minimize cutaneous lupus erythematosus exacerbations. Since the initial success of the treatment of lupus erythematosus with quinacrine Atabrine by Prokoptchouk 1a and Popoff and Kutinscheff 1b and later by Page, 2 in Europe, attempts have been made to find other less toxic antimalarial agents. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Treatment of discoid lupus erythematosus with chloroquine Treatment of Systemic Lupus Erythematosus An Update., Treatment of Cutaneous Lupus Erythematosus Pompe glycogen storage and hydroxychloroquineWhat does plaquenil do to the immune systemHydroxychloroquine for lupus nephritis Treatment of discoid lupus erythematosus Begin treatment with the elimination of foci of chronic infection in the body, the normalization of endocrine disorders. Eliminate other irritating and provoking factors, such as direct sunlight, radiation therapy, cold, drafts, external skin damage. Discoid lupus erythematosus Symptoms and treatment of.. CHLOROQUINE DIPHOSPHATE IN TREATMENT OF DISCOID LUPUS.. REFERENCES - UpToDate. User Reviews for Plaquenil to treat Systemic Lupus Erythematosus. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Systematic administration of chloroquine in discoid lupus erythematosus reduces skin lesions via inhibition of angiogenesis. The treatment of discoid cutaneous lupus erythematosus was, until recently, very unsatisfactory. The disease not infrequently persists for many years, with intermittent exacerbations and partial remissions unrelated to any particular type of treatment. The only measure of regular value has been.