It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. What is the drug hydroxychloroquine Antiboptics and plaquenil Contraindications. Known hypersensitivity to, or retinal or visual field changes associated with quinoline compounds; psoriasis, porphyria, long-term therapy in children; pregnancy category C. Safe use in juvenile arthritis or lactation is not established. Plaquenil hydroxychloroquine has a good safety record in lupus pregnancy, and is usually continued if needed to control maternal lupus. Management and Monitoring. Lupus pregnancy should be timed to coincide with a period of good disease control if at all possible. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil pregnancy category c Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy., Lupus and Pregnancy Johns Hopkins Lupus Center Treatment for chloroquine resistant vivax malariaPlaquenil and heart disease Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Plaquenil hydroxychloroquine sulfate dosing, indications.. Drug Safety in Pregnant & Nursing Women.. Hydroxychloroquine Oral Route Description and Brand Names.. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. My rheumatologist prescribed me Plaquenil, he’s assured me it’s safe during pregnancy and I plan to contact my OB tomorrow to get her thoughts. I’m just so anxious because I want the pain to go away and enjoy my pregnancy as much as one can but I also don’t want to do anything at all to harm my unborn baby.