I would think the drug has aggravated a pre-existing condition. There may be another drug that would not cause your GERD. Taking plaquenil with imuran Chloroquine resistente bakterien disseration How long for plaquenil rash to go away My doctor wants me to start taking Plaquenil tomorrow. I have read some of your comments about nausea, heartburn, indigestion, and hair loss. I am wondering how long it will take to get any of these side effects if at all after I start Plaquenil? One day, one week, one month, one year? Thank. So far it’s been okay, no major side effects. Except today I started having some heartburn after taking it. It says on the bottle I can’t take an antacid for at least four hours after taking the Plaquenil. Hi Gidget. I was taking some meds for GERD a few years back and my doc said that it was fine as long as the two were not taken in the same dose. In other words, wait an hour or two after the Pepcid to take your other meds. Something to do with ant-acid blocking absorption of the other meds. Just a thought. SO glad the pepcid helped. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil is the brand name for the prescription drug hydroxychloroquine. What can i take for heartburn with plaquenil Having issues with Plaquenil -, Plaquenil and heartburn rheumatoid Plaquenil retinal toxicity dosageHydroxychloroquine porphyria cutanea tarda mechanismBlack cohosh and plaquenilOct for plaquenil icd10 However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. It's recommended you wait at least four hours after taking hydroxychloroquine before you take an indigestion remedy. Hydroxychloroquine Side-effects, uses, time to work. Plaquenil and Pepcid -. Gastroscopy, have to stop medication 10 days before? - UK.. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction. Popular Heartburn Meds Can Have. I have been on Plaquenil about a year now and I have not noticed any heartburn but I also take Aciphex for unrelated GI problems and have for many years. So I can not help you there. I have expereinced the pain and burning sensation in the breastbone and shoulder blade area as well.