It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Hydroxychloroquine lyme treatment Side effects of long term plaquenil use Chloroquine chemo Children's doses are based on body weight as prescribed by the doctor. To help reduce stomach upset, hydroxychloroquine should be taken with a meal or a glass of milk. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. This drug definitely does not cause weight gain or bloat, thank goodness! Steroids are what are infamous for doing that. I've seen some people say it causes stomach/gi problems, but I personally have had no side effects at all. And like Veej said, it's one of the safest long term drugs for lupus. want to know good stuff about plaquenil. The plaquenil has caused a weight gain of about 20-25 pounds for me. Since I was diagnosed with MCTD a year ago, Plaquenil has been the only medication besides eye supplements, thyroid meds - been stable for years, and most recently Evoxac that I have been given. It is also used to treat acute and chronic rheumatoid arthritis. Hydroxychloroquine is used to treat discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE or lupus). Plaquenil cause weight gain Rx Side Effects New Plaquenil Guidelines and More - American., Want to know good stuff about plaquenil - HealthBoards Medication for rheumatoid arthritis instead of plaquenilPrimaquine chloroquine interactionDoes chloroquine kill cyanobacteria My weight gain is from the steroids I'm certain and not the Plaquenil. Are you on anything else to treat your lupus other than the Plaquenil? If you're on steroids that can be whats causing you to gain weight. I can't offer any advice on losing the weight if you come off the Plaquenil. Plaquenil and weight gain -. Plaquenil & Weight Gain/Loss -. Medrol, Plaquenil and weight gain - Sclero Forums MAIN.. Find information about common, infrequent and rare side effects of Plaquenil Oral. These medications tend to cause insomnia, increased appetite, and water retention,” she says—a perfect storm for weight gain. Dr. Hall adds that, in her experience, around 75 percent of. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.