Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Allergic reaction when changed from hydroxychloroquine to plaquenil Why take plaquenil with food Apr 02, 2019 This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in three days. The dosage for adults of low body weight and for infants and children should be determined as follows First dose 10 mg base per kg but not exceeding a single dose of 600 mg base. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Chloroquine was administered to the mice in the first group as 20 mg/kg b.w. once a day for four consecutive days. Quinine at a dose of 20 mg/kg b.w. was given to the mice in the second group for the first day and 10 mg/kg b.w. for the second to fourth day. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine dose Chloroquine Oral Uses, Side Effects, Interactions, Pictures., Chloroquine Oral Uses, Side Effects, Interactions. Plaquenil psoriasisCan you take berberine with plaquenilPlaquenil macular octPercentage of people with hair loss on plaquenilDifference between hydroxychloroquine and chloroquine To treat malaria Chloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. To treat amebiasis Chloroquine is given in a high starting dose for 2 days followed by a smaller dose for 2 to 3 weeks. Chloroquine Uses, Side Effects, Dosage & Interactions. Comparative study of chloroquine and quinine on malaria rodents and.. CHLOROQUINE Drug BNF content published by NICE. To treat malaria Chloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. To treat amebiasis Chloroquine is given in a high starting dose for 2 days followed by a smaller dose for 2 to 3 weeks. You may be given other medications to help prevent further infection. However, being they contain less usable "chloroquine base" means you have to dose more which becomes more expensive. See below for more details In most cases, 250 mg tablets have an equivalence of 150 mg chloroquine base, and 500 mg tablets have an equivalence of 300 mg chloroquine base. Results of one study indicate that chloroquine may exhibit nonlinear dose dependent pharmacokinetics. In this study, administration of a single 500 mg oral dose of chloroquine resulted in a peak serum concentration of 0.12 ug/mL, and administration of a single 1 g oral dose of the drug resulted in a peak serum concentration of 0.34 ug/mL.