One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine sulfate usp 200 mg Hydroxychloroquine and thyroid Icd10cm code for plaquenil This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Drusen are small yellow or white deposits that form in the retina or on the optic nerve head. They are accumulations of extracellular material that build up in the eye. The detection of a few drusen is normal with aging eyes, with most people over the age of 40 having at least some drusen. PLAQUENIL should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects. Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil drusen deposits Peripheral retinal drusen more common in Alzheimer’s Modern., Drusen Deposits in the Eye - Chloroquine side effects depression Basal Linear Deposit and Large Drusen Are Specific for Early Age-Related Maculopathy Christine A. Curcio, PhD; C. Leigh Millican Objective. Basal Linear Deposit and Large Drusen Are Specific for Early.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Dry macular degeneration - Diagnosis and treatment - Mayo.. Dry AMD occurs when small, age-related deposits called drusen form at the basement of the retina, or the retinal pigment epithelial layer. These age-related changes effect up to 11 million people in the United States. I have had a large number of drusen in my retina for about 10 year. The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied, no. Drusen, from the German word for node or geode singular, "Druse", are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the presence of a few small "hard" drusen is normal with advancing age, and most people over 40 have some hard drusen. However, the presence of larger and more numerous drusen.