There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. Hydroxychloroquine sulfate usp 200 mg Plaquenil dosage guidelines For patients taking hydroxychloroquine to prevent malaria Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. A month after coming off I had an eye exam and all was normal. It was a little tough, those two weeks, but all in all, the experience was not terrible, and it eventually ended with me non the worse. I continued to be on prednisone as my primary treatment for the sarcoidosis and am still on it despite multiple tries to come off. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Being able to stop joint damage can lessen pain and mean a better quality of life. You can also put off joint damage, and in some cases, you can do more than just slow it down. How to come off hydroxychloroquine Coming off Hydroxychloroquine I went to see my, Plaquenil Withdrawal – Life As An Anomaly Hydroxychloroquine and rheumatoid arthritisPlaquenil chemoDoes plaquenil help with allergies OverviewMedical useAdverse effectsInteractionsOverdosePharmacology Hydroxychloroquine - Wikipedia. Hydroxychloroquine Plaquenil. Hydroxychloroquine MedlinePlus Drug Information. With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. You can also put off joint damage, and in some cases, you can do more than just slow it down. Being able to stop joint damage can lessen pain and mean a better quality of life. Hydroxychloroquine is one of the medications that can be a valuable part of your treatment plan.