Eye test for plaquenil toxicity

Discussion in 'Canadian Pharmacies Online' started by hook, 13-Mar-2020.

  1. sale Moderator

    Eye test for plaquenil toxicity


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Fundus changes on biomicroscopy, including bull's eye maculopathy, are indicative of fairly advanced hydroxychloroquine-induced retinal toxicity which is largely irreversible despite cessation of the medication.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Eye test for plaquenil toxicity

    Hydroxychloroquine screening, Recommendations on Screening for Chloroquine and.

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  6. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity.

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    Good question. Back on nov 5 i think it was i felt there was a really good discussion about hydroxychlorouine & eye tests here. One of us posted detailed info about her experience & the different types of eye test anyone on plaquenil etc would probably be best to have, and the frequency. Macular Society Eye screening for patients taking hydroxychloroquine. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. The actual incidence of retinal toxicity from hydroxychloroquine is difficult to pin down because there is usually a long time between being started on the drug and the start of any identifiable retinal toxicity. The overall rate of probable retinal toxicity is in the range of 1 of every 200 people treated.

     
  7. Alexwweb User

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroquine Oral Route Proper Use - Mayo Clinic Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs Chloroquine MedlinePlus Drug Information
     
  8. fomind New Member

    How long is chloroquine half life when I treat a cell line. How long is chloroquine half life when I treat a cell line for an autophagy study? I treated some cell lines with 25 mM Chloroquine for 48h without adding fresh chloroquine.

    Chloroquine - Wikipedia