I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil lupus remission How long will plaquenil stay in your system Is it common practice to wean off plaquenil hydroxychloroquine for undifferentiated connective tissue disease if it didn't improve sx? Methotrexate was added & helps. Steroid drug withdrawal facts; Are steroids anti-inflammatories? What are steroid withdrawal symptoms and signs? How do you taper off steroids? Do they affect your adrenal glands? What tests do doctors use to diagnose withdrawal from steroids? Which types of specialists treat steroid withdrawal symptoms? What is the treatment for steroid. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Weaning off plaquenil Stopping plaquenil. DailyStrength, Steroid Drug Withdrawal Symptoms, Treatment & Prognosis Review of optometry plaquenil guidelinesPlaquenil retina Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. Taking Plaquenil for Rheumatoid Arthritis. Can you quit plaquenil cold turkey, or have to wean. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. I was told it helps to minimize the progression of the arthritis and helps to lessen flare ups. Happily, going off plaquenil quelled the worst of my psoriasis, so the overall trade-off was eventually worth it for me. It wasn't very clear from your post whether it was the primary care doctor or the rheumatologist who wants him to decrease the plaquenil.