The most common side effect associated with its use is retinal toxicity, which may be irreversible. Therefore, it is pertinent to know the findings, risk factors, and screening tests necessary to prevent retinal damage. Plaquenil and eye photosensitivity Chloroquine cellular toxicity Hydroxychloroquine sulphate over the counter Changes In The Visual Field; Decreased Blood Platelets; Deposits On The Eye; Erythema Multiforme, A Type Of Allergic Skin Reaction; Glucose-6-Phosphate Dehydrogenase G6PD Deficiency Anemia. Section was added to the Plaquenil drug label with information regarding use with digoxin, insulin or diabetic drugs, drugs that prolong QT interval and other arrhythmogenic drugs, mefloquine and other drugs known to lower the convulsive threshold, antiepileptics, methotrexate, cyclosporine, Biltricide. The changes are most often permanent, but in some cases, vision has improved. Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. During the first five years of use, the rate of toxicity was found to be 0.7%, rising significantly to more than 1% after five to seven years of use. The prevalence of retinal toxicity has varied among different studies. Visual field changes with plaquenil New Plaquenil Guidelines -, Plaquenil hydroxychloroquine – New Warnings Plaquenil ibdChloroquine aralen costWill hydroxychloroquine help osteoarthritisDoes hydroxychloroquine make you gain weightKinds o generic hydroxychloroquine A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil Side Effects on Your Eyes and Vision. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Visual fields. In early cases of Plaquenil toxicity, an early indicator of damage is the appearance of a paracentral scotoma seen on automated visual field testing in the absence of fundus changes. 18 Each of the testing strategies can be used to detect early toxicity changes, but the presentation of the visual field effects will vary. Due to the central area being depressed in the 24-2 and 30-2 testing strategies, it is difficult to discern the central 2-degree field of sparing seen in the. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Jan 01, 2020 A baseline ocular examination is recommended within the first year of starting Plaquenil. The baseline exam should include best corrected distance visual acuity BCVA, an automated threshold visual field VF of the central 10 degrees with retesting if an abnormality is noted, and spectral domain ocular coherence tomography SD-OCT.