I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. How longbto take plaquenil after alcohol Plaquenil main side effects Chloroquine contraindications I have psoriatic arthritus. I take an injection weekly of methotrexate. I have done this for several years now. I want to quit taking it. Can I safely quit it "cold turkey?" i.e. immediately or should I take steps of some sort? I too suddenly stopped taking mine cold turkey. Not out of choice, but because I lost my insurance and couldn't get refills. About a month after I started feeling awful! The plaquenil had been helping so much. Its now about three minths later and I'm very afraid that I'm in renal failure. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopping plaquenil cold turkey Stopping Methotrexate • Johns Hopkins Arthritis Center, Fear of Plaquenil - Autoimmune Disorders - MedHelp Hydroxychloroquine medlineplusIs hydroxychloroquine safeWhat is hydroxychloroquine used for Jul 24, 2010 Unfortunately, it's not a good idea to stop methotrexate "cold turkey.". Some people experience no side effects to suddenly stopping taking this medication, but it does have the potential for creating an intense RA flare. The goal of medication is to protect your joints and other systems in the body internal organs, such as the heart. What Are The Side Effects Of Stopping Methotrexate?. Hydroxychloroquine Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Withdrawal – Life As An Anomaly. Jun 19, 2013 It didn't take me long to feel the effects of stopping. I guess I didn't realize how much it was helping me. So far I feel More tired Breathing is more difficult Feels like I am drowning Arms and legs are tingling Numb hands and feet Headache I don't know if this is the result of stopping Plaquenil or just how my Sarcoidosis is presenting. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can.