Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Tell me about plaquenil Plaquenil makes my stomach bleed Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. One of the most serious side effects is retinopathy generally with chronic use. 1 15 People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. RARE side effects A Change In Vision. Acquired Chromatopsia, A Change In Color Vision. Irritability. Loss Of Muscle Coordination. Low Energy. Mood Changes. Muscle Tremors. Muscle Weakness. Nightmares. Nystagmus, A Condition With Involuntary Eye Movements. Ringing In The Ears. Sensation Of. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil visual side effects Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Hydroxychloroquine - Wikipedia Chloroquine phoenix cells Visual changes and loss of vision are potential hydroxychloroquine side effects, although they most commonly occur in individuals who have taken high doses of hydroxychloroquine for long periods. Physicians will generally recommend an eye exam every six months for patients taking hydroxychloroquine long-term. Hydroxychloroquine Plaquenil Success, Reviews and Side.. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Hallucination, visual is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Lasix, and have Essential hypertension. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects.