One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Molecular weight of chloroquine phosphate Plaquenil and chronic fatigue syndrome Hydroxychloroquine plaquenil outcome for lupus patients Click to email this to a friend Opens in new window Click to share on Twitter Opens in new window Click to share on Pocket Opens in new window In obvious toxicity, the nasal inner subfield showed more thinning than the temporal inner subfield at 12 months after drug cessation p = 0.018, 95 % CI −1 to −8 μm. Conclusions Once HCQ retinopathy is diagnosed and the medication is discontinued, structural retinal changes commonly occur. Plaquenil Toxicity both Eyes - Partial Bull's Eye - Discontinued 6 Years ago SD-OCT Spectral domain optical coherence tomography 1098 views 82-year-old woman was on Plaquenil from 1976 from 2005, 200 mg a day. It was discontinued because of abnormal visual fields 6 years ago. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct images of plaquenil toxicity Hydroxychloroquine Plaquenil Toxicity and., Expanded spectral domain-OCT findings in the early. Plaquenil cause alopeciaCan hydroxychloroquine cause staphylococcus aureus utiPlaquenil and red eyesPlaquenil lucite avis When this thinning is translated into an OCT map, a bulls-eye pattern of thinning is manifested, as shown in the image entitled "Time Domain OCT Map in Hydroxychloroquine Toxicity". The patient shown here is the same one shown in the image "Asymmetric Hydroxychloroquine Plaquenil Retinal Toxicity". Time Domain OCT in Hydroxychloroquine Plaquenil Toxicity.. Plaquenil Toxicity - Mild - Partial Bull's Eye Maculopathy.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Spectral Domain Optical Coherence Tomography SD OCT uses light to capture micrometer-resolution, three-dimensional images from within optical scattering media. Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. it is the photoreceptors that are the targets of hydroxychloroquine toxicity. Currently, one of the primary functional screening tests recommended for the evaluation of Plaquenil retinal toxicity is 10-2 white stimulus automated visual fields; however, research shows Asian patients benefited from 24-2 or 30-2 visual fields, given that toxicity often manifests changes beyond the macula in these patients. 9 Because spectral-domain optical coherence tomography SD-OCT is readily accessible and able to detect early structural damage prior to clinical funduscopic findings. Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal.