Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil and cns Hydroxychloroquine sulphate bp 200mg Chloroquine effect on cell lysis Malaria chloroquine tablets Daily treatment with hydroxychloroquine, particularly when weight-based dosing is used, has been accepted as a major risk factor for hydroxychloroquine retinopathy Tables 1,2; however, the type of weight measurement used in these calculations IBW versus ABW is a matter of contention. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil retinopathy treatment Chloroquine and Hydroxychloroquine Toxicity Treatment., Hydroxychloroquine Plaquenil Toxicity and. Chloroquine therapeutic class Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Chloroquine retinopathy - Wikipedia. Hydroxychloroquine retinopathy A review of imaging. Plaquenil - FDA prescribing information, side effects and uses. Hydroxychloroquine retinopathy, it is important you ask your GP or specialist to refer you for screening. Progression of retinopathy. In most cases it is expected that stopping the hydroxychloroquine treatment will stop the. retinopathy worsening. If the condition does progress, a person may. experience significant loss of vision over time. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Apr 10, 2019 When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 months of treatment. While using Plaquenil, you may need frequent blood tests and vision exams.