Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil dosing instructions How does chloroquine phosphate work Plaquenil generic drug Plaquenil cream Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hey all. I hope everyone is having a great day. I have a question to ask anyone on plaquenil. After taking it, does it make you feel all of sudden really tired? I recently started taking it in September and it seems like after about 5-10 minutes of taking it, I feel super tired and sleepy. I. Well, I work full time and am tired a lot, but I think it's normal at my age - So I think, if your fatigue condition has not been better with your current medication, you may want to try something else. My dr said the Plaquenil takes long time to start working, but for some people, like me, it has a great long term benefit. Good luck! Plaquenil is used to treat other types of infections too. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil makes me tired Will you have Fatigue with Plaquenil - eHealthMe, Does Plaquenil make you tired? DailyStrength Plaquenil story on cbs tonightPlaquenil medscapeNabumetone lupus hydroxychloroquineChloroquine po 300 mg daily Hi ellilu, I too am taking Plaquenil and although it has helped with the more severe joint pains and stiffness I am also always fatigued. I was noticing that I'm tired putting a sweater over my head my arms feel tired, showering, driving, getting in and out of my car is a bit tiring. These things were once so normal and now they tire me out. Is extreme fatigue a side effect of Plaquenil - NRAS. Plaquenil for fatigue and pain DailyStrength. Plaquenil as lyme treatment Anti-Inflammatories discussions.. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. I've been on Plaquenil 200mg 2 x day for 6 days and I am so tired. Slept 11 hours last night and I am still tired. Diagnosed with Psoriatic or Rheumitoid Arthritis Dr. not sure yet. I didn't have significant fatigue previously, so I assume it's the medicine. I also had a steriod shot in swollen joint, but I don't think that would cause fatique. Re plaquenil for vasculitis They are getting ready to start the methotrexate this week on Wednesday to go with the plaquenil. I went get a base line from the opthalmologist before I started the plaquenil and he told me to do a simple test everyday and see him twice a year and it would be ok and get caught early if it starts to bother my eyes.